At Indigo Clinic, we believe in transparency, education, and results—especially when it comes to the most innovative skin treatments we offer. One of our most exciting regenerative therapies is polynucleotide (PN) treatment. But despite its growing popularity, there are still a lot of myths and misconceptions surrounding it.
Let’s break it down and clarify why polynucleotides are a game-changer in advanced skincare, and how they can transform your skin from the inside out.
You’ve likely heard of rejuvenating facials—treatments designed to refresh the skin and reduce visible signs of ageing. These work on the surface to enhance appearance temporarily.
Polynucleotides are different. They are regenerative.
Derived from highly purified salmon DNA, PNs work deeper in the skin to stimulate natural repair and cellular renewal. They encourage fibroblast activity, improve hydration, and support long-term skin health—rebuilding from the inside out for visible, long-lasting improvements.
“They’re just like Botox.”
Botox works by relaxing muscles to reduce dynamic wrinkles. Polynucleotides, however, work at the cellular level to improve hydration, collagen synthesis, and skin quality over time.
“They deliver instant volume like fillers.”
PNs don’t add instant volume. Instead, they encourage natural repair and regeneration, gradually improving firmness, hydration, and elasticity.
“They’re the same as hyaluronic acid.”
Both hydrate, but hyaluronic acid retains moisture while PNs activate fibroblasts, boost skin healing, and promote collagen and elastin production.
“They’re unsafe because they come from fish sperm.”
Polynucleotides are derived from salmon DNA through a rigorous purification process, making them sterile, safe, and biocompatible. They’ve been used in medicine for decades with an excellent safety profile.
At Indigo Clinic, we use high-quality, clinically validated products like Dermafocus’s Plinest Eye, specifically designed for delicate areas such as the under-eye.
“They can completely reverse ageing.”
PNs don’t stop the ageing process, but they significantly slow down visible signs of ageing by supporting the skin’s natural repair mechanisms.
“Only mature skin can benefit.”
Polynucleotides are suitable for all ages. Younger clients use them to treat acne scarring or pigmentation, while mature clients benefit from their anti-ageing and restorative effects.
One of the common questions about injectables is whether they move from the treatment site.
Polynucleotides remain exactly where they are placed. Once injected, they integrate into the tissue, supporting local skin repair, hydration, and regeneration. Over time, they break down naturally and safely, leaving behind visibly improved skin.
If you want a skin treatment that is natural, regenerative, and clinically backed, polynucleotides are a smart, modern choice. Whether you're concerned about fine lines, dullness, acne scars, or early signs of ageing, PNs offer a gentle but powerful way to encourage long-term skin health.
📍 Indigo Clinic at Looks London, 20 Main Ave, Northwood Moor Park, HA6 2HJ
📍 Indigo Clinic at Forest House, 8 Park Avenue, Watford, WD18 7HP
📞 Call us: 07756924108
📧 Email: info@indigoclinic.co.uk
Book your consultation today at Indigo Clinic, and let’s build a personalised plan that helps your skin repair, regenerate, and glow naturally.
